Sarilumab

Product Description: Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis[1][2].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]McCarty D, et al. Efficacy and safety of sarilumab in patients with active rheumatoid arthritis. Ther Adv Musculoskelet Dis. 2018;10(3):61-67./[2]Xu C, et al. Population Pharmacokinetics of Sarilumab in Patients with Rheumatoid Arthritis. Clin Pharmacokinet. 2019;58(11):1455-1467.

Molecular Weight: N/A

Compound Purity: 98.37

Research Area: Inflammation/Immunology; Cancer

Solubility: H2O

Target: Interleukin Related

• Artikelnummer: MEXHY-P9916-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P9916-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK