Product Description: Tafolecimab (IBI-306) is a human lgG2 monoclonal antibody that specifically binds PCSK-9 and reduces LDL-C levels by inhibiting PCSK-9-mediated endocytosis of the LDL receptor, which in turn enhances clearance of LDL-C and leads to a reduction in LDL-C levels. Tafolecimab may be used in studies of hypercholesterolaemia[1].
Applications: Neuroscience-Neuromodulation
Formula: N/A
References: [1]Y Cui, et al. Tafolecimab, a novel potential long-acting PCSK9 monoclonal antibody: efficacy and safety in healthy and hypercholesterolemia subjects .European Heart Journal, Volume 41, Issue Supplement_2, November 2020.
CAS Number: 2225109-03-3
Molecular Weight: N/A
Compound Purity: 95.04
Research Area: Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: PCSK9