Tamrintamab, CAS 2148325-59-9

Product Description: Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 (DPEP3 or MBD3). DPEP3 is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Martín-Sabroso C, et al. Antibody-Antineoplastic Conjugates in Gynecological Malignancies: Current Status and Future Perspectives. Pharmaceutics. 2021 Oct 15;13(10):1705. /[2]Wiedemeyer W R, et al. Abstract NT-113: SC-003, AN ANTIBODY-DRUG CONJUGATE TARGETING DIPEPTIDASE 3, EXHIBITS POTENT ANTI-TUMOR ACTIVITY IN PATIENT-DERIVED XENOGRAFT MODELS OF HIGH GRADE SEROUS OVARIAN CANCER[J]. Clinical Cancer Research, 2019, 25(22_Supplement): NT-113-NT-113.

CAS Number: 2148325-59-9

Molecular Weight: N/A

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Antibody

• Artikelnummer: MEXHY-P99506-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99506-1
• Green Labware: Nein
• Verpackungseinheit: 1mg
• Mengeneinheit: STK