Tenatumomab, CAS 1412891-40-7

Product Description: Tenatumomab (ST2146) is a murine monoclonal antibody against tenascin-C. And tenascin-C, the large extracellular glycoprotein, is overexpressed in cancer. Tenatumomab has been used for Pretargeted Antibody Guided Radioimmunoresearch (PAGRIT), and delivering radionuclides to tumors via PAGRIT and direct 131Iodine labeling approach[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Giannini G, et al. Synthesis and preliminary in vitro evaluation of DOTA-Tenatumomab conjugates for theranostic applications in tenascin expressing tumors. Bioorg Med Chem. 2019 Aug 1;27(15):3248-3253. /[2]De Santis R, et al. Low and high tenascin-expressing tumors are efficiently targeted by ST2146 monoclonal antibody. Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2191-6.

CAS Number: 1412891-40-7

Molecular Weight: N/A

Compound Purity: 95.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• Artikelnummer: MEXHY-P99566-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99566-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Konjugat: Unconjugated