Tengonermin, CAS 1960461-99-7

Product Description: Tengonermin (ARENEGYR) is a vascular-targeting agent consisting of the human Tumour Necrosis Factor-α (TNF-α) conjugated with the CNGRCG peptide. Tengonermin increases penetration of intratumoral chemotherapy and T-cell infiltration by modifying the tumour microenvironment[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Valentinis B, et, al. Mechanism of Action of the Tumor Vessel Targeting Agent NGR-hTNF: Role of Both NGR Peptide and hTNF in Cell Binding and Signaling. Int J Mol Sci. 2019 Sep 12;20(18):4511. /[2]Gregorc V, et, al. NGR-hTNF in combination with best investigator choice in previously treated malignant pleural mesothelioma (NGR015): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet Oncol. 2018 Jun;19(6):799-811.

CAS Number: 1960461-99-7

Molecular Weight: N/A

Research Area: Cancer

Solubility: H2O

Target: TNF Receptor

• Artikelnummer: MEXHY-P99565-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99565-1
• Verpackungseinheit: 1mg
• Mengeneinheit: STK
• Konjugat: Unconjugated