Teplizumab, CAS 876387-05-2

Product Description: Teplizumab (MGA-031) is a Fc receptor non-binding anti-human CD3 monoclonal antibody. Teplizumab reduces the loss of beta-cell function. Teplizumab can be used in the research of type 1 diabetes[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: N/A

References: [1]Kevan C Herold, et al. An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes. N Engl J Med. 2019 Aug 15;381(7):603-613. /[2]Frank Waldron-Lynch, et al. I Analysis of FcR non-binding anti-CD3 mAb in humanized mice identifies novel human gut tropic cells with regulatory function that are found in patients. Sci Transl Med. 2012 Jan 25;4(118):118ra12. /[3]Brygida Bisikirska, et al. TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs. J Clin Invest. 2005 Oct;115(10):2904-13.

CAS Number: 876387-05-2

Molecular Weight: N/A

Compound Purity: 99.90

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: CD3

• Artikelnummer: MEXHY-P99222-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99222-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK