Volociximab, CAS 558480-40-3

Product Description: Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 (EC50=0.2 nM). Integrin α5β1 is a major fibronectin receptor involved in angiogenesis. Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs)[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Bhaskar V, et al. Volociximab, a chimeric integrin alpha5beta1 antibody, inhibits the growth of VX2 tumors in rabbits. Invest New Drugs. 2008 Feb;26(1):7-12. /[2]Ramakrishnan V, et al. Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent. J Exp Ther Oncol. 2006;5(4):273-86.

CAS Number: 558480-40-3

Molecular Weight: 145.5 kDa (Average)

Compound Purity: 95.47

Research Area: Cancer; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Integrin

• Artikelnummer: MEXHY-P99333-10
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99333-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK