Vopratelimab, CAS 2039148-04-2

Product Description: Vopratelimab (JTX-2011) is a humanized immunoglobulin G1-kappa agonist monoclonal antibody that pecifically binds to the Inducible CO-Stimulator of T cells (ICOS). Vopratelimab retains species cross-reactivity with affinities of 0.93 nM to hICOS, 0.46 nM to cynomolgus ICOS, 3.7 nM to rat ICOS, and 0.64 nM to mICOS. Vopratelimab has antitumor immune response[1].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Hanson A, et, al. ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models. PLoS One. 2020 Sep 24;15(9):e0239595.

CAS Number: 2039148-04-2

Molecular Weight: N/A

Compound Purity: 95.00

Research Area: Cancer; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Others

• Artikelnummer: MEXHY-P99382-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P99382-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK