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Human EGFR Protein (Recombinant His, C-Terminal)
Human EGFR Protein (Recombinant His, C-Terminal)
Artikelnummer
LIFLS-G27253-1
Verpackungseinheit
1 mg
Hersteller
LSBio
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Presentation: Lyophilized from PBS
Description: EGF Receptor,also known as ERBB, ERBB1 and HER1, is a type I transmembrane protein belonging to the tyrosine protein kinase family. It binds to a subset of EGF family ligands, including EGF, TGF-alpha, amphiregulin, EPGN, BTC, EREG and HBEGF. Ligand binding triggers receptor homo- or hetero-dimerization, which induces downstream kinase activation, tyrosine phosphorylation and cell signaling. EGF receptor signaling has been shown to regulate cell proliferation, differentiation, motility and apoptosis.
Synonyms: EGFR, EGF Receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1
Recommended Storage: Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
Protein Tag: His, C-Terminal
Protein Type: Recombinant
Reconstitution Instructions: Reconstitute in sterile ddH20 or PBS at 100 ug/ml.
Purification: Greater than 95% by SDS-PAGE
Predicted Molecular Weight: 95-115 kDa (SDS-PAGE)
Description: EGF Receptor,also known as ERBB, ERBB1 and HER1, is a type I transmembrane protein belonging to the tyrosine protein kinase family. It binds to a subset of EGF family ligands, including EGF, TGF-alpha, amphiregulin, EPGN, BTC, EREG and HBEGF. Ligand binding triggers receptor homo- or hetero-dimerization, which induces downstream kinase activation, tyrosine phosphorylation and cell signaling. EGF receptor signaling has been shown to regulate cell proliferation, differentiation, motility and apoptosis.
Synonyms: EGFR, EGF Receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1
Recommended Storage: Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
Protein Tag: His, C-Terminal
Protein Type: Recombinant
Reconstitution Instructions: Reconstitute in sterile ddH20 or PBS at 100 ug/ml.
Purification: Greater than 95% by SDS-PAGE
Predicted Molecular Weight: 95-115 kDa (SDS-PAGE)
| Artikelnummer | LIFLS-G27253-1 |
|---|---|
| Hersteller | LSBio |
| Hersteller Artikelnummer | LS-G27253-1 |
| Green Labware | Nein |
| Verpackungseinheit | 1 mg |
| Mengeneinheit | STK |
| Reaktivität | Human |
| Human Gene ID | 1956 |
| Wirt | Hamster |
| Produktinformation (PDF) |
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| MSDS (PDF) |
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