Human HBEGF / HB EGF Protein (Recombinant)

Presentation: Lyophilized from PBS

Description: Proheparin-binding EGF-like growth factor (HB-EGF), also known as DTR, DTS and HEGFL, is a member of the EGF family of mitogens. It is expressed in macrophages, monocytes, endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle cells, epithelial cells and keratinocytes. Compared to EGF, HB-EGF binds the EGF receptor with higher affinity and is thus more mitogenic, probably due to its ability to bind to heparin and heparin sulfate proteoglycans. HB-EGF has been reported to act as a diphtheria toxin receptor, mediating endocytosis of the bound toxin.

Synonyms: HBEGF, Dtr, DTS, DTSF, HEGFL, Diphtheria Toxin Receptor

Recommended Storage: Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

Protein Type: Recombinant

Reconstitution Instructions: Reconstitute in ddH2O or PBS at 100 µg/ml.

Purification: Greater than 95% by SDS-PAGE and HPLC

Predicted Molecular Weight: 12-14 kDa (SDS-PAGE)

• Artikelnummer: LIFLS-G27105-5
• Hersteller: LSBio
• Hersteller Artikelnummer: LS-G27105-5
• Green Labware: Nein
• Verpackungseinheit: 5 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Human Gene ID: 1839
• Wirt: Hamster