PTEN Blocking Peptide

Formulation: 200 µg of peptide in 200 µl TBS, pH 7.4, with 0.1% BSA and 0.02% sodium azide

Shelf life (days): 1095

Notes: To be used in conjunction with Cayman’s PTEN polyclonal antibody (Catalog No. 10005059) to block protein-antibody complex formation during immunochemical analysis of PTEN · PTEN dephosphorylates proteins and lipids such as AKT and phosphatidylinositol 3,4,5-triphosphate (PIP3) and therefore functions as a key regulatory enzyme in a central signal transduction pathway. PTEN is expressed in almost all tissues of the body as a 403 amino acid protein with an estimated molecular weight of 47 kDa, however the actual migration observed on western blot may vary among distinct samples.{13064} PTEN interacts with many other proteins to regulate cell division and migration as well as promoting apoptosis when necessary.{13065} Mutation of PTEN results in many human cancers including melanoma and prostate carcinoma.{12235,13040}

• Artikelnummer: CAY10007073
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10007073-1
• Verpackungseinheit: 1 Piece
• Mengeneinheit: STK
• Methode: Western Blotting, Immunohistochemistry