Soluble Epoxide Hydrolase Blocking Peptide

Formulation: 200 μg of peptide in 200 μl TBS, pH 7.4, with 0.1% BSA and 0.02% sodium azide

Shelf life (days): 1095

Notes: To be used in conjunction with Cayman’s Soluble Epoxide Hydrolase polyclonal antibody (Catalog No.10010146) to block protein-antibody complex formation during analysis for soluble epoxide hydrolase. The metabolism of exogenous and endogenous epoxides relies in part upon the activity of soluble epoxide hydrolase (sEH).{830} The relevance of sEH to hypertension and inflammation makes it a potentially useful clinical drug target. Specifically, the conversion of epoxyeicosatrienoic acids (EpETrEs, EETs) by sEH to the corresponding dihydroxy eicosatrienoic acids (DiHETrEs, DHETs) diminishes their vasodilator activity.{12607} Inhibitors of sEH may therefore have clinical utility for treating hypertension and systemic inflammation.{14065,14072} Cayman · s polyclonal antibody is useful for monitoring the quantity and distribution of sEH.

• Artikelnummer: CAY10010147
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10010147-1
• Verpackungseinheit: 1 Piece
• Mengeneinheit: STK
• Methode: Western Blotting