G6PD Antibody - middle region : FITC

G6PD Antibody - middle region : FITC
Artikelnummer
AVIARP58469_P050FITC
Verpackungseinheit
100μl
Hersteller
Aviva Systems Biology

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Conjugation: FITC: Fluorescein Isothiocyanate

Description of Target: G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human G6PD

Key Reference: Langbein,S., (2008) Int. J. Cancer 122 (11), 2422-2428

Molecular Weight: 57kDa

Peptide Sequence: Synthetic peptide located within the following region: VTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRI

Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.

Protein Name: Glucose-6-phosphate 1-dehydrogenase

Protein Size: 515

Purification: Affinity Purified
Mehr Informationen
Artikelnummer AVIARP58469_P050FITC
Hersteller Aviva Systems Biology
Hersteller Artikelnummer ARP58469_P050-FITC
Green Labware Nein
Verpackungseinheit 100μl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus), Sheep (Ovine), Rabbit, Dog (Canine), Guinea Pig, Cow (Bovine), Horse (Equine)
Klonalität Polyclonal
Methode Western Blotting
Human Gene ID 2539
Wirt Rabbit
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