ACTN1 Antibody - N-terminal region : Biotin

ACTN1 Antibody - N-terminal region : Biotin
Artikelnummer
AVIARP58413_P050-Btn
Verpackungseinheit
100μl
Hersteller
Aviva Systems Biology

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Conjugation: Biotin

Description of Target: Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACTN1

Key Reference: Li,Q., (2007) J. Neurochem. 103 (6), 2391-2400

Molecular Weight: 103kDa

Peptide Sequence: Synthetic peptide located within the following region: DHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQ

Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.

Protein Name: Alpha-actinin-1

Protein Size: 892

Purification: Affinity Purified
Mehr Informationen
Artikelnummer AVIARP58413_P050-Btn
Hersteller Aviva Systems Biology
Hersteller Artikelnummer ARP58413_P050-Biotin
Green Labware Nein
Verpackungseinheit 100μl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus), Rabbit, Dog (Canine), Guinea Pig, Cow (Bovine), Zebrafish, Horse (Equine)
Klonalität Polyclonal
Methode Western Blotting, Immunohistochemistry
Human Gene ID 87
Wirt Rabbit
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