CloneID: A12A3
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original version of this antibody was raised by immunizing a mouse with HPV58 and HPV59 VLPs.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG2b format, created for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P26535
Specificity Statement: This antibody is specific for the DE loops of two adjacent HPV58 L1 monomers.
Application Notes (Clone): The original version of this antibody was used for surface plasmon resonance on HPV58 and HPV59 pentamers. The structure of the antibody was determined using x-ray diffraction. Further the structure of the antibody was determined using cryo-EM (Zhihai et al., 2017; PMID:28951471).
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