Conjugation: HRP: Horseradish Peroxidase
Description of Target: The function of C2orf25 remains unknown.Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to adenosylcobalamin in mitochondria and to methylcobalamin in cytoplasm is necessary for homeostasis of methylmalonic acid and homocysteine. C2ORF25 encodes a protein involved in an early step of cobalamin metabolism (Coelho et al., 2008 [PubMed 18385497]).[supplied by OMIM].
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C2orf25
Key Reference: Coelho,D., (2008) N. Engl. J. Med. 358 (14), 1454-1464
Molecular Weight: 33kDa
Peptide Sequence: Synthetic peptide located within the following region:
RAEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHLGFSVDDLGCCKVIProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Methylmalonic aciduria and homocystinuria type D protein, mitochondrial
Protein Size: 296
Purification: Affinity Purified