Conjugation: HRP: Horseradish Peroxidase
Description of Target: The first mRNA transcript isolated for C2orf3 gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). C2orf3 belongs to the GCF family. It is a factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C2orf3
Key Reference: Anthoni,H., (2007) Hum. Mol. Genet. 16 (6), 667-677
Molecular Weight: 89kDa
Peptide Sequence: Synthetic peptide located within the following region:
SEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: GC-rich sequence DNA-binding factor 2
Protein Size: 781
Purification: Affinity Purified