CD3e(CRIS-7), 1mg/mL

Description: Recognizes the epsilon chain of CD3 (Workshop V; Code: CD03.09), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: CRIS-7

Entrez Gene ID: 916

Immunogen: Stimulated human leukocytes

Expected AB Applications: Functional studies (published for clone)

Verified AB Applications: Flow (surface) (verified)/IF (verified)

Z-Antibody Applications: Functional studies (published)/Flow, surface (verified)/IF (verified)

• Artikelnummer: BTMBNUM1050-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM1050-50
• Green Labware: Nein
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human, Monkey (Primate)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Flow Cytometry, Functional Studies
• Isotyp: IgG2a kappa
• Wirt: Mouse