GAD65 antibody (MSVA-602M) HistoMAX™

Clone Name: MSVA-602M

Light Chain: Kappa

Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.

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Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 65

Positive Control: Pancreas: A strong GAD2 staining should be seen in pancreatic islet cells.

Negative Control: Colon: GAD2 immunostaining should be absent in all cell types

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]

Uniprot ID: Q05329

Antigen Species: Human

Immunogen: Recombinant human GAD2 (GAD65) protein fragment (around aa 6-99)

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: glutamate decarboxylase 2

• Artikelnummer: GTX04477-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04477-500
• Green Labware: Nein
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2b
• Human Gene ID: 2572
• Wirt: Mouse