Conjugation: HRP: Horseradish Peroxidase
Description of Target: LTB4DH functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. It has no activity towards PGE1, PGE2 and PGE2-alpha. LTB4DH catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LTB4DH
Key Reference: Chou,W.L., (2007) J. Biol. Chem. 282 (25), 18162-18172
Molecular Weight: 36kDa
Peptide Sequence: Synthetic peptide located within the following region:
VRTKTWTLKKHFVGYPTNSDFELKTSELPPLKNGEVLLEALFLTVDPYMRProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Prostaglandin reductase 1
Protein Size: 329
Purification: Affinity Purified