Occludin antibody (MSVA-415M) HistoMAX™

Clone Name: MSVA-415M

Light Chain: Kappa

Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.

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Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 59

Positive Control: Colon: A strong membranous occludin staining of epithelial cells should be seen with a particularly strong staining at the apical/luminal membranes.

Negative Control: Colon: All non-epithelial and non-endothelial cells must not show any occludin staining.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]

Uniprot ID: Q16625

Antigen Species: Human

Immunogen: ecombinant fragment of human Occludin protein (around aa 282-415)

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: occludin

• Artikelnummer: GTX04461-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04461-500
• Green Labware: Nein
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1
• Human Gene ID: 100506658
• Wirt: Mouse