PE-conjugated Anti-4-1BB Ligand antibody(DM68); Rabbit mAb

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9:4-1BB; which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9:4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene; TNFSF9:4-1BBL; has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines; and is thought to be involved in T cell-tumor cell interaction.

Description: PE-conjugated Anti-4-1BB Ligand antibody(DM68); Rabbit mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 41% BSA

Target: 4-1BB Ligand

Uniprot ID: P41273

Usage: Research use only

Clone ID: DM68

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100

• Artikelnummer: DMADME100068P-100
• Hersteller: DIMA Biotechnology
• Hersteller Artikelnummer: DME100068P-100
• Verpackungseinheit: 100 test
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: Rabbit IgG
• Wirt: Rabbit
• Konjugat: Conjugated, PE (Phycoerythrin)