PE-conjugated Anti-CSF1R antibody(DM107); Rabbit mAb

Background: The protein encoded by this gene is the receptor for colony stimulating factor 1; a cytokine which controls the production; differentiation; and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1:PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL); HL cell lines and anaplastic large cell lymphoma.

Description: PE-conjugated Anti-CSF1R antibody(DM107); Rabbit mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 78% BSA

Target: CSF1R

Uniprot ID: P07333

Usage: Research use only

Clone ID: DM107

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100

• Artikelnummer: DMADME100107P-100
• Hersteller: DIMA Biotechnology
• Hersteller Artikelnummer: DME100107P-100
• Verpackungseinheit: 100 test
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Flow Cytometry
• Isotyp: Rabbit IgG
• Wirt: Rabbit
• Konjugat: Conjugated, PE (Phycoerythrin)