Conjugation: HRP: Horseradish Peroxidase
Description of Target: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RASGRF1
Key Reference: Iguchi,T., (2007) Int. J. Oncol. 31 (2), 285-291
Molecular Weight: 54kDa
Peptide Sequence: Synthetic peptide located within the following region:
RELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Ras-specific guanine nucleotide-releasing factor 1
Protein Size: 489
Purification: Affinity Purified
Specificity#: Predicted to recognized both human RASGRF1 isoforms (145, 55kD)