S100 beta antibody (MSVA-490R) HistoMAX™

S100 beta antibody (MSVA-490R) HistoMAX™
Artikelnummer
GTX04404-S-100
Verpackungseinheit
100 μl
Hersteller
GeneTex

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Clone Name: MSVA-490R

Product Description: This antibody was validated on 76 different Normal and cancerTissues by IHC-P.

Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 11

Positive Control: Appendix: Schwann cells of peripheral nerves and adipocytes should show a strong, predominantly cytoplasmic S100B staining.

Negative Control: Appendix: Smooth muscle and epithelial cells must not show any S100B staining.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]

Uniprot ID: P04271

Antigen Species: Human

Immunogen: Recombinant full-length human S100B protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: S100 calcium binding protein B
Mehr Informationen
Artikelnummer GTX04404-S-100
Hersteller GeneTex
Hersteller Artikelnummer GTX04404-S-100
Green Labware Nein
Verpackungseinheit 100 μl
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunohistochemistry (paraffin)
Isotyp IgG
Human Gene ID 6285
Wirt Rabbit
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