Transgelin antibody

Application Note: WB: 1:1000-1:2000. ICC/IF: 1:100-1:500. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 23

Form: Liquid

Buffer (with preservative): PBS, 150 mM NaCl, 50% glycerol, 0.02% sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]

Uniprot ID: Q01995

Antigen Species: Human

Immunogen: A synthesized peptide derived from human TAGLN(Accession Q01995), corresponding to amino acid residues E170-S201.

Purification: Purified by antigen-affinity chromatography

Conjugation: Unconjugated

Full Name: transgelin

• Artikelnummer: GTX04760-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04760-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 6876
• Wirt: Rabbit