UPK1B antibody (MSVA-734M) HistoMAX™

UPK1B antibody (MSVA-734M) HistoMAX™
Artikelnummer
GTX04450-500
Verpackungseinheit
500 μl
Hersteller
GeneTex

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Clone Name: MSVA-734M

Light Chain: Kappa

Product Description: This antibody was validated on 76 different Normal and cancerTissues by IHC-P.

Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 30

Positive Control: Urinary bladder: A strong membranous and cytoplasmic UPK1b immunostaining should be seen in the urothelium (the staining can be limited to the top cell layers or equally involve all cell layers).

Negative Control: Colon: UPK1b immunostaining should be absent in all cells of the colon mucosa.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot ID: O75841

Antigen Species: Human

Immunogen: Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: uroplakin 1B
Mehr Informationen
Artikelnummer GTX04450-500
Hersteller GeneTex
Hersteller Artikelnummer GTX04450-500
Green Labware Nein
Verpackungseinheit 500 μl
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunohistochemistry (paraffin)
Isotyp IgG2b
Human Gene ID 7348
Wirt Mouse
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