Storage: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Abbreviation: CD66b
Target Synonym: CGM,NCA,Carcinoembryonic Antigen CGM,Non-Specific Cross-Reacting Antigen NCA,CEACAM,CEACAM8,CD66b,CD67,CGM6,NCA-95,Carcinoembryonic Antigen CGM6,Carcinoembryonic antigen-related cell adhesion molecule 8,CD67 Antigen,Non-Specific Cross-Reacting Antigen NCA-95,CGM6,NCA-95,Carcinoembryonic antigen gene family member 6,Carcinoembryonic antigen related cell adhesion molecule 8,CD 66b,CD 67,CD66b antigen,CEACAM 8,CEAM8,CGM 6,NCA 95,NCA95,Nonspecific cross reacting antigen NCA 95,Nonspecific cross reacting antigen NCA95
Background: Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8) is a single chain, GPI-anchored, highly glycosylated protein which belongs to the immunoglobulin superfamily and the carcinoembryonic antigen(CEA) family. CEACAM8 is expressed by neutrophils and eosinophils, and serves as a binding partner for CEACAM-6 and Galectin-3. It contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. Mature human CEACAM8 is a 287 amino acid GPI-linked glycoprotein. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migRation, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells.
Immunogen: Recombinant Human CD66b protein
Buffer: PBS, pH 7.2. Contains 0.05% proclin 300.
Dilution: FCM 2 μg/mL(1×105-5×105 cells)
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