Elab Fluor 488 Anti-Human CD193/CCR3 Antibody(5E8), Mouse, Monoclonal

Abbreviation: CD193/CCR3

Target Synonym: CC CKR3; MIP1-alpha receptor like-2; eotaxin receptor;CCR;C-C chemokine receptor type 3;

Conjugation: Elab Fluor® 488

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Clone NO.: 5E8

UNIProt ID: P51677

Background: CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+?hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.

Concentration: 5 uL/Test

• Artikelnummer: ELSE-AB-F1303L-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-F1303L-20
• Green Labware: Nein
• Verpackungseinheit: 20 Tests
• Mengeneinheit: PAK
• Reaktivität: Human
• Methode: Flow Cytometry
• Isotyp: Mouse IgG2b κ
• Human Gene ID: 1232
• Wirt: Mouse