Goat anti-Human Apo E Antibody HRP Conjugated

Stock Concentration: 1 mg/ml

Conjugate Type: HRP

Buffer: Phosphate Buffered Saline (PBS) containing 0.2% BSA and 0.05% Pro-Clean 400

Shelf Life: 1 year from date of receipt

Protein ID: NP_000032.1

Uniprot ID: P02649

Background: Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

Immunogen: Human Apolipoprotein E

• Artikelnummer: BEYA81-118P
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A81-118P
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting, ELISA
• Isotyp: Whole IgG
• Human Gene ID: 348
• Wirt: Goat