TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL

Description: Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, with BSA

Concentration: 0.2 mg/mL

Storage buffer: PBS, 0.05% BSA, 0.05% azide

Product Origin: Animal - Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)

Clone: TLE1/2946R

Entrez Gene ID: 7088

Immunogen: Recombinant human TLE1 fragment (aa 175-338) (exact sequence is proprietary)

Verified AB Applications: IHC (FFPE) (verified)

Z-Antibody Applications: IHC, FFPE (verified)

• Artikelnummer: BTMBNUB2946-100
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUB2946-100
• Verpackungseinheit: 100 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Immunohistochemistry
• Isotyp: IgG
• Wirt: Rabbit