Conjugation: HRP: Horseradish Peroxidase
Description of Target: VGLL1 is a specific coactivator for the mammalian TEFs. The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses a TEA/ATTS DNA-binding domain. In Drosophila, Scalloped (Sd) interacts with Vestigial (Vg) to form a complex, which binds DNA through the Sd TEA/ATTS domain. The Sd-Vg heterodimer is a key regulator of wing development, which directly controls several target genes and is able to induce wing outgrowth when ectopically expressed.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human VGLL1
Key Reference: Ross,M.T., (2005) Nature 434 (7031), 325-337
Molecular Weight: 29kDa
Peptide Sequence: Synthetic peptide located within the following region:
RPQESAARENGNPGQIAGSTGLLFNLPPGSVHYKKLYVSRGSASTSLPNEProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Transcription cofactor vestigial-like protein 1
Protein Size: 258
Purification: Affinity Purified