1-Methylxanthine-d3, CAS 1216430-61-3

Product Description: 1-Methylxanthine-d3 is deuterated labeled 1-Methylxanthine (HY-W008449). 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].

Applications: Cancer-programmed cell death

Formula: C6H3D3N4O2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Algharrawi KH, et al. Direct conversion of theophylline to 3-methylxanthine by metabolically engineered E. coli. Microb Cell Fact. 2015 Dec 21;14:203./[3]Youn H, et al. 1-Methylxanthine enhances the radiosensitivity of tumor cells. Int J Radiat Biol. 2009 Feb;85(2):167-74.

CAS Number: 1216430-61-3

Molecular Weight: 169.16

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug Metabolite;Endogenous Metabolite;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-W008449S2-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W008449S2-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK