5-Aminosalicylic acid-13C6, CAS 1189709-96-3

Product Description: 5-Aminosalicylic acid-13C6 is the 13C labeled 5-Aminosalicylic Acid[1]. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[2][3][4].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C 13C6H7NO3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Dammann K, et al. PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2349-60./[3]Fang HM, et al. 5-aminosalicylic acid in combination with Nimesulide inhibits proliferation of colon carcinoma cells in vitro. World J Gastroenterol. 2007 May 2813(20):2872-7./[4]Rousseaux C, et al. The 5-aminosalicylic acid antineoplastic effect in the intestine is mediated by PPARγ. Carcinogenesis. 2013 Nov34(11):2580-6.

CAS Number: 1189709-96-3

Molecular Weight: 159.09

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite;NF-κB;PAK;PPAR

• Artikelnummer: MEXHY-15027S2-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15027S2-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK