Amiodarone-d5 (hydrochloride)

Product Description: Amiodarone-d5 hydrochloride is deuterated labeled Amiodarone (HY-14187). Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM.

Applications: Neuroscience-Neuromodulation

Formula: C25H25D5ClI2NO3

References: [1]Singh, B.N. and E.M. Vaughan Williams, The effect of amiodarone, a new anti-anginal drug, on cardiac muscle. Br J Pharmacol, 1970. 39(4): p. 657-67./[2]Rosenbaum, M.B., et al., Clinical efficacy of amiodarone as an antiarrhythmic agent. Am J Cardiol, 1976. 38(7): p. 934-44./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 686.80

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Autophagy;Isotope-Labeled Compounds;Potassium Channel

• Artikelnummer: MEXHY-14187S1-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-14187S1-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK