Product Description: Apocynin-d3 is the deuterium labeled Apocynin[1]. Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM[2][3][4].
Applications: Cancer-programmed cell death
Formula: C9H7D3O3
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Stolk J,et al. Am J Respir Cell Mol Biol, 1994, 11(1), 95-102./[3]Stefanska J, et al. Mediators Inflamm, 2008, 106507./[4]Impellizzeri D et al. Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation. Biochem Pharmacol. 2011 Mar 181(5):636-48.
CAS Number: 80404-23-5
Molecular Weight: 169.19
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Apoptosis;Autophagy