Artemisinin-13C,d4

Product Description: Artemisinin-13C,d4 is 13C and deuterated labeled Artemisinin (HY-B0094). Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].

Applications: COVID-19-anti-virus

Formula: C14 13CH18D4O5

References: [1]Lin SP, et al. Artemisinin Prevents Glutamate-Induced Neuronal Cell Death Via Akt Pathway Activation. Front Cell Neurosci. 2018 Apr 20;12:108./[2]Zeng Z, et al. Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway. Redox Biol. 2017 Apr 4;12:625-633./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 287.35

Research Area: Cancer; Infection; Neurological Disease

Solubility: 10 mM in DMSO

Target: Akt;Ferroptosis;HCV;Isotope-Labeled Compounds;Parasite

• Artikelnummer: MEXHY-B0094S3-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0094S3-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK