Artesunate-d4, CAS 1316753-15-7

Product Description: Artesunate-d4 is deuterium labeled Artesunate. Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).

Applications: Cancer-Kinase/protease

Formula: C19H24D4O8

References: [1]Ilamathi M, et al. Artesunate as an Anti-Cancer Agent Targets Stat-3 and Favorably Suppresses Hepatocellular Carcinoma. Curr Top Med Chem. 2016;16(22):2453-63./[2]Lisewski AM, et al. Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate. Cell. 2014 Aug 14;158(4):916-928./[3]Wang B, et al. Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51. Cancer Biol Ther. 2015;16(10):1548-56./[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 1316753-15-7

Molecular Weight: 388.45

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Ferroptosis;Isotope-Labeled Compounds;Parasite;STAT;Virus Protease

• Artikelnummer: MEXHY-N0193S1-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0193S1-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK