Asenapine-13C,d3, CAS 2747915-30-4

Product Description: Asenapine-13C,d3 is 13C and deuterated labeled Asenapine (HY-10121). Asenapine (Org 5222), an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine can be used in the research of schizophrenia and bipolar disorder[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C20 13CH17D3ClNO5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]M Shahid, et al. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol. 2009 Jan;23(1):65-73./[3]Olivia Frånberg, et al. Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia. Psychopharmacology (Berl). 2008 Feb;196(3):417-29.

CAS Number: 2747915-30-4

Molecular Weight: 405.85

Research Area: Endocrinology; Neurological Disease

Solubility: 10 mM in DMSO

Target: 5-HT Receptor;Adrenergic Receptor;Dopamine Receptor;Histamine Receptor;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-10121S2-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-10121S2-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK