Brexpiprazole-d8, CAS 1427049-21-5

Product Description: Brexpiprazole-d8 is a deuterium labeled Brexpiprazole (OPC-34712). Brexpiprazole, an atypical antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine receptor (Ki=0.12 nM and 0.3 nM, respectively). Brexpiprazole is also a 5-HT2A receptor antagonist (Ki=0.47 nM)[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C25H19D8N3O2S

References: [1]Ishima T, et al. Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors. Eur Neuropsychopharmacol. 2015 Apr;25(4):505-11./[2]Yoshimi N, et al. Improvement of dizocilpine-induced social recognition deficits in mice by brexpiprazole, a novel serotonin-dopamine activity modulator. Eur Neuropsychopharmacol. 2015 Mar;25(3):356-64.

CAS Number: 1427049-21-5

Molecular Weight: 441.62

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: 5-HT Receptor;Dopamine Receptor

• Artikelnummer: MEXHY-15780S-500UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15780S-500UG
• Green Labware: Nein
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK