Calcitriol-d3, CAS 128723-16-0

Product Description: Calcitriol-d3 is the deuterium labeled Calcitriol[1]. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist[2][3][4][5].

Applications: Cancer-programmed cell death

Formula: C27H41D3O3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Wang G, et al. Calcitriol Inhibits Cervical Cancer Cell Proliferation Through Downregulation of HCCR1 Expression. Oncol Res. 2014;22(5-6):301-9./[3]Santos-Martínez N, et al. Calcitriol restores antiestrogen responsiveness in estrogen receptor negative breast cancer cells: a potential new therapeutic approach. BMC Cancer. 2014 Mar 2914:230./[4]Dong J, et al. Calcitriol restores renovascular function in estrogen-deficient rats through downregulation of cyclooxygenase-2 and the thromboxane-prostanoid receptor. Kidney Int. 2013 Jul84(1):54-63./[5]Chou CL, et al. Beneficial effects of calcitriol on hypertension, glucose intolerance, impairment of endothelium-dependent vascular relaxation, and visceral adiposity in fructose-fed hypertensive rats. PLoS One. 2015 Mar 1610(3):e0119843.

CAS Number: 128723-16-0

Molecular Weight: 419.65

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite;VD/VDR

• Artikelnummer: MEXHY-10002S1-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-10002S1-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK