Canrenone-d4

Product Description: Canrenone-d4 is deuterium labeled Canrenone. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.

Applications: Neuroscience-Neuromodulation

Formula: C22H24D4O3

References: [1]Caligiuri A, et al. Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells. Gastroenterology. 2003 Feb;124(2):504-20./[2]Erbler HC, et al. Effect of spironolactone and its main metabolite canrenone on the renin-angiotensin-aldosterone-system during long-term treatment in rats. Acta Endocrinol (Copenh). 1979 Jan;90(1):147-56./[3]Erbler HC, et al. On the mechanism of the inhibitory action of the spirolactone SC 9376 (aldadiene) on the production of corticosteroids in rat adrenals in vitro. Naunyn Schmiedebergs Arch Pharmacol. 1973;277(2):139-49./[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Molecular Weight: 344.48

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite;Isotope-Labeled Compounds;Mineralocorticoid Receptor

• Artikelnummer: MEXHY-B1438S1-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B1438S1-5
• Green Labware: Nein
• Verpackungseinheit: 5mg
• Mengeneinheit: STK