Carbamazepine-d8, CAS 1538624-35-9

Product Description: Carbamazepine-d8 is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent, with an IC50 of 131 μM[1][2].

Applications: Cancer-programmed cell death

Formula: C15H4D8N2O

References: [1]Willow, M. and W.A. Catterall, Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine. Mol Pharmacol, 1982. 22(3): p. 627-35./[2]Okada, M., et al., Biphasic effects of carbamazepine on the dopaminergic system in rat striatum and hippocampus. Epilepsy Res, 1997. 28(2): p. 143-53./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 1538624-35-9

Molecular Weight: 244.32

Research Area: Cancer; Neurological Disease

Solubility: 10 mM in DMSO

Target: Autophagy;Mitophagy;Sodium Channel

• Artikelnummer: MEXHY-B0246S2-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0246S2-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK