Citric acid-13C3, CAS 302912-06-7

Product Description: Citric acid-13C3 is the 13C labeled Citric acid[1]. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[2][3][4].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C3 13C3H8O7

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Chen X, et al. Study on injury effect of food additive citric acid on liver tissue in mice. Cytotechnology. 2014 Mar;66(2):275-82./[3]Chen X, Lv Q, Liu Y, Deng W. Effects of the food additive, citric acid, on kidney cells of mice. Biotech Histochem. 2015 Jan90(1):38-44. /[4]Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct33(10):4411-20.

CAS Number: 302912-06-7

Molecular Weight: 195.10

Solubility: 10 mM in DMSO

Target: Antibiotic;Apoptosis;Endogenous Metabolite

• Artikelnummer: MEXHY-N1428S3-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N1428S3-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK