Clofibric acid-d4, CAS 1184991-14-7

Product Description: Clofibric acid-d4 is the deuterium labeled Clofibric acid. Clofibric acid (Chlorofibrinic acid), the pharmaceutically active metabolite of lipid regulators Clofibrate, Etofibrate and Etofyllinclofibrate, is a PPARα agonist which exhibits hypolipidemic effects. Clofibric acid also is an herbicide[1][2][3].

Formula: C10H7D4ClO3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Forman BM, et, al. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4312-7./[3]Salgado R, et, al. Biodegradation of clofibric acid and identification of its metabolites. J Hazard Mater. 2012 Nov 30;241-242:182-9./[4]Kawashima Y, et, al. Increased activity of stearoyl-CoA desaturation in liver from rat fed clofibric acid. Biochim Biophys Acta. 1982 Dec 13;713(3):622-8.

CAS Number: 1184991-14-7

Molecular Weight: 218.67

Research Area: Others

Solubility: 10 mM in DMSO

Target: Drug Metabolite;Isotope-Labeled Compounds;PPAR

• Artikelnummer: MEXHY-B1415S-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B1415S-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK