Deoxycholic acid-d6

Product Description: Deoxycholic acid-d6 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.

Formula: C24H34D6O4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Somm E, et al. β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue. JCI Insight. 2017 Apr 20;2(8). pii: 91809./[3]Wang X, et al. Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in micedependent on c-Myc expression. Cancer Med. 2017 Apr;6(4):788-797.

Molecular Weight: 398.61

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite;G protein-coupled Bile Acid Receptor 1;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-N0593S2-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0593S2-5
• Green Labware: Nein
• Verpackungseinheit: 5mg
• Mengeneinheit: STK