Dihydrouracil-13C4,15N2, CAS 360769-22-8

Product Description: Dihydrouracil-13C4,15N2 is the 13C and 15N labeled Dihydrouracil[1]. Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient[2][3].

Formula: 13C4H6 15N2O2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Henricks LM, et, al. Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers. Br J Clin Pharmacol. 2018 Dec;84(12):2761-2769./[3]Jacobs BAW, et, al. The impact of liver resection on the dihydrouracil:uracil plasma ratio in patients with colorectal liver metastases. Eur J Clin Pharmacol. 2018 Jun;74(6):737-744.

CAS Number: 360769-22-8

Molecular Weight: 120.06

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite

• Artikelnummer: MEXHY-W012926S-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W012926S-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK