Diosmetin-d3, CAS 1189728-54-8

Product Description: Diosmetin-d3 is the deuterium labeled Diosmetin. Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity with an IC50 of 40 μM in HepG2 cell.

Formula: C16H9D3O6

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. /[2]Liu B, et al. Diosmetin induces apoptosis by upregulating p53 via the TGF-β signal pathway in HepG2 hepatoma cells. Mol Med Rep. 2016 Jul;14(1):159-64./[3]Yu G, et al. Diosmetin ameliorates the severity of cerulein-induced acute pancreatitis in mice by inhibiting the activation of the nuclear factor-κB. Int J Clin Exp Pathol. 2014 Apr 15;7(5):2133-42.

CAS Number: 1189728-54-8

Molecular Weight: 303.28

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Cytochrome P450;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-N0125S-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0125S-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK