Dolasetron-d5

Product Description: Dolasetron-d5 is deuterated labeled Dolasetron (HY-B0750). Dolasetron (MDL-73147) is a 5-HT3 receptor antagonist with potential for treatment of chemotherapy-induced nausea and vomiting.

Applications: Cancer-programmed cell death

Formula: C19H15D5N2O3

References: [1]Faria C, et al. Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis. Am Health Drug Benefits. 2014 Jan;7(1):50-8./[2]Schwartzberg L, et al. Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV). Support Care Cancer. 2014 Feb;22(2):469-77./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Molecular Weight: 329.40

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: 5-HT Receptor;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-B0750S1-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0750S1-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK