(E)-Ferulic acid-d3, CAS 860605-59-0

Product Description: (E)-Ferulic acid-d3 is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1].

Formula: C10H7D3O4

References: [1]Fong Y, et al. Inhibitory effect of trans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability. Chin Med. 2016 Oct 1;11:45./[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

CAS Number: 860605-59-0

Molecular Weight: 197.20

Compound Purity: 99.0

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Bcl-2 Family;Endogenous Metabolite;Ferroptosis;β-catenin

• Artikelnummer: MEXHY-N0060BS-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N0060BS-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK